Houston, we have a problem with our critical infrastructure in space. While our individual dependency on space has also grown, safeguarding space still remains an issue. Critical infrastructure and services like 5G connectivity and GPS navigation rely on space-based assets to carry out their daily functioning. This dependency makes space-based assets potential targets for description and espionage by strategic adversaries, as well as a potential target for criminal groups.  So how can we defend and secure this critical backbone? In many ways, questions of securing critical infrastructure and bolstering cybersecurity in space systems are similar to those we face in securing terrestrial assets. But are there key differences in how we must secure space systems? What are those similarities and differences? Who has jurisdiction? Where do we still have gaps, both in terms of our own capabilities and understanding the threats posed by adversaries?